Oral submucous fibrosis is a chronic, insidious, disabling disease involving oral mucosa, the oropharynx, and rarely, the larynx. It is exclusively reported in Indian population.
The disease is characterised by blainching and stiffness of the oral mucosa, trismus, burning sensation in the mouth, hypomobility of the soft palate and tongue, loss of gustatory sensation, and occasionally, mild hearing loss due to blockage of Eustachian tube.
A variety of aetiological factors including capsaicin, betal nut alkaloids, hypersensitivity, autoimmunity, genetic and malnutrition.
The disease can be classified clinically into two phases (1) An eruptive phase, characterised by formation of erythema, vesicles, ulceration and a burning sensation in the mouth. (2) The fibrosis induction phase, characterised by the disappearance of the vesicles and healing of the ulcers by fibrosis. The burning sensation decreases and blanching and stiffness of the oral and oropharyngeal mucosa occur.
complications include oral cancer
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TEETH Care Centre Dental Hospital, Ahmedabad
